Both Newham’s MPs have voted against prime minister Theresa May’s Brexit deal.

Their votes contributed to the biggest loss for a British government in modern political history.

East Ham MP Stephen Timms said: “It shows that the government does not command the confidence of Parliament.

“The centrepiece of its programme has been comprehensively rejected, including by the great majority of its own backbench MPs.

“Parliament should now vote, at the end of the debate today, that it has no confidence in the government.”

West Ham MP Lyn Brown tweeted before the vote that she would not be voting for the government’s deal, saying: “It would leave the people I represent much worse off. A no deal is utterly irresponsible.

May’s plan was voted down 432 votes to 202, a margin of 230.